Mouse Secondary Antibodies
Biotium EGFR(H9B4), CF740 conjugate, 0.1mg/mL
This MAb reacts with a cytoplasmic domain of EGFR. EGFR is a type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, βcellulin & epiregulin.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Biotium CD40, Mouse(FGK45.5), CF405S conjugate, 0.1mg/mL
Upon binding to its ligand CD154, CD40 acts as a costimulatory molecule for the activation of B cells, dendritic cells, monocytes, and other APCs. CD40 plays roles in B cell activation, differentiation, proliferation and Ig isotype switching as well as dendritic cell maturation. FGK4. 5 can be used for blocking of CD40/CD154 interaction and forin vitroandin vivoactivation of CD40 expressing APCs. This MAb is shown to indirectly activate natural killer (NK) cells, producing significant antitumor and anti-metastatic effects. Effective in boosting immune responses against infectious agents and can potentially be used to treat chronic autoimmune inflammatory processes. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower
Biotium CD40 / TNFRSF5 / CD40L-Receptor(T8P2G4*A6), CF640R conjugate, 0.1mg/mL
This antibody is specific for the soluble form of CD40. It is a receptor on antigen-presenting cells of the immune system and is essential for mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. AT-hook transcription factor AKNA is reported to coordinately regulate the expression of this receptor and its ligand, which may be important for homotypic cell interactions. Adaptor protein TNFR2 interacts with this receptor and serves as a mediator of the signal transduction. The interaction of this receptor and its ligand is found to be necessary for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis. CD40 is expressed on B-lymphocytes, follicular dendritic cells, bone marrow-derived dendritic cells, thymic epithelium, and interdigitating cells in the T-cell zones of secondary lymphoid org
Biolegend PerCP/FireTM 780 anti-mouse CD
PerCP/Fire 780 anti-mouse CD20 [SA275A11] Isotype Rat IgG2b Reactivity Mouse Apps FC Size 100 g
Cayman Chemical α-Linolenic Acid, Purity: ≥98%, CAS: 463-40-1, 100 mg
An essential ω-3 polyunsaturated fatty acid found in plants; converted to eicosapentaenoic, docosapentaenoic, and docosahexaenoic acids, catabolized via fatty acid β-oxidation for energy or the synthesis of saturated and monounsaturated fatty acids, or stored in adipose tissue in vivo; dietary consumption is positively associated with a moderately lower risk of cardiovascular disease
Biolegend Spark RedTM 718 anti-mouse Sig
Spark Red 718 anti-mouse Siglec-G [SH1] Isotype Mouse IgG1 Reactivity Mouse Apps FC Size 100 g
AdipoGen IgG mouse pAb HRP
Polyclonal Antibody. Reacts with mouse IgG1, IgG2a, IgG2b and IgG3. Source Goat. Applications IHC, WB. Liquid. In PBS containing 50% glycerol. The anti-IgG mouse, pAb HRP is cross-absorbed against mouse IgM and IgA, pooled human sera and purified human paraproteins and affinity-purified on pooled mouse IgG covalently linked to agarose.
Cayman Chemical MS-PPOH, Purity: ≥98%, CAS: 206052-02-0, 50 mg
Arachidonic acid is converted by microsomal CYP450 enzymes to a variety of epoxides, ω-1 and ω-hydroxylated compounds via what is known as the epoxidase pathway.{313,403,823} MS-PPOH is a selective inhibitor of the epoxygenation reactions catalyzed by specific CYP450 isozymes.{8589} MS-PPOH inhibits the formation of arachidonate 11,12-epoxides by CYP4A2 and CYP4A3 enzymes with an IC50 value of 13 µM, but has no effect on the formation of 20-HETE, the ω-hydroxylation product of CYP4A1.{8588}
Cayman Chemical α-Linolenic Acid, Purity: ≥98%, CAS: 463-40-1, 50 mg
An essential ω-3 polyunsaturated fatty acid found in plants; converted to eicosapentaenoic, docosapentaenoic, and docosahexaenoic acids, catabolized via fatty acid β-oxidation for energy or the synthesis of saturated and monounsaturated fatty acids, or stored in adipose tissue in vivo; dietary consumption is positively associated with a moderately lower risk of cardiovascular disease
Cayman Chemical MK-571 (sodium salt), Purity: ≥95%, CAS: 115103-85-0, 1 mg
A CysLT1 receptor antagonist (Ki = 2.1 nM in a radioligand binding assay using isolated human lung membranes); inhibits contractions induced by LTD4 or LTE4 in histamine-primed isolated guinea pig trachea (pA2s = 9.4 and 9.1, respectively), but not contractions induced by LTC4 in histamine-primed isolated guinea pig trachea at 190 nM; inhibits LTD4-induced calcium mobilization in COS-7 cells expressing the human CysLT1 receptor at 100 nM; improves tissue damping and elasticity, markers of lung function, and decreases IL-4 and IL-5 levels in BALF in a mouse model of ovalbumin-induced asthma at 5 mg/kg
Cayman Chemical (−)-(α)-Kainic Acid (hydrate), Purity: ≥98%, CAS: 58002-62-3, 10 mg
A cyclic analog of L-glutamate; binds to GluK1, GluK2, GluK3, GluK4, and GluK5 (Kis = 75.9, 12.7, 32.8, 4.7, and 15 nM, respectively); induces calcium influx and membrane depolarization, as well as glutamate release, in rat brain synaptosomes at 5 mM; induces chromatin condensation and nuclear membrane fragmentation in primary neonatal cerebellar granule neurons at 100 µM; induces convulsive behavior in rats (ED50 = 0.51 nmol/animal) and induces seizures in mice (CD50 = 0.39 nmol/animal); has been commonly used to induce seizures in rodents
Cayman Chemical α-Guanidinoglutaric Acid, Purity: ≥98%, CAS: 73477-53-9, 100 mg
A linear mixed-type inhibitor of nNOS having a Ki value of 2.69 µM; normally present in small quantities in the cerebral cortex of cats with increased levels following seizure
Sigma Aldrich Fine Chemicals Biosciences Monoclonal Anti Actin alph
smooth muscle actin a smooth muscle cell-specific protein is also known as aortic smooth muscle or a smooth muscle actin (SMA SMactin SM-actin ASMA). It belongs to the actin family.It is predominantly found in cells of the smooth muscle lineages. It has been reported that smooth muscle actin was also found in certain non-muscle cells in particular fibroblasts i.e. myofibroblasts. Actin a conserved eukaryotic protein is the major cytoskeletal component and is expressed as six different isoforms in mammals and birds. It is mapped to human chromosome 10q23.31.The antibody reacts with normal and neoplastic human vascular and visceral smooth muscle cells. It reacts with normal myoepithelial cells pericytes eye lens cells hair follicle cells and certain stromal cells in the intestine testis lymphoid organs liver ovary and bone marrow. The antibody also reacts with stromal myofibroblasts in hypertrophic scars and in neoplastic tissues. smooth muscle actin is tr
Cayman Chemical α-Linolenic Acid, Purity: ≥98%, CAS: 463-40-1, 250 mg
An essential ω-3 polyunsaturated fatty acid found in plants; converted to eicosapentaenoic, docosapentaenoic, and docosahexaenoic acids, catabolized via fatty acid β-oxidation for energy or the synthesis of saturated and monounsaturated fatty acids, or stored in adipose tissue in vivo; dietary consumption is positively associated with a moderately lower risk of cardiovascular disease